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This can occur at any time during treatment. Possible side effects of indomethacin include:. Nausea and vomiting. Indigestion and stomachache. Headache. Dizziness. Fatigue.
Sleepiness. Ringing in the earsSerious side effects can occur with indomethacin.If you have any of these side effects, stop taking indomethacin and call your doctor right away. A typical dose of indomethacin for rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis is 75 milligrams (mg) two or three times a day, but your doctor will try to find the lowest dose that works for you.Indomethacin comes in regular capsules, extended-release capsules, liquid form, and suppositories.Don't open or crush the extended-release capsules, and mix the liquid thoroughly. Take indomethacin with food or after a meal.Treatment for shoulder pain may continue for one or two weeks, but should stop as soon as pain goes away.In 2014, the FDA approved a low-dose version of indomethacin: 20-mg and 40-mg capsules sold under the brand name Tivorbex.This version of the drug is made of smaller particles of indomethacin that dissolve more quickly. Indomethacin OverdoseAn overdose of indomethacin can cause nausea, vomiting, severe headache, dizziness, confusion, and tiredness.Severe symptoms can include numbness, tingling, and seizure.If you think you have taken an overdose, or if someone else may have overdosed on indomethacin, call a poison control center at 1-800-222-1222 or call 911. Missed Dose of IndomethacinTake indomethacin exactly as directed by your doctor.
Don't take more or less.If you miss a dose of indomethacin, take the missed dose as soon as you remember.But if it's almost time for your next dose, skip the missed dose and continue your regular dosing schedule.Don't double your dose to make up for the missed one. A: Indomethacin (Indocin) can cause blood glucose levels to rise. Indomethacin can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole).
These conditions can be fatal, and gastrointestinal effects can occur without warning at any time while you are taking an NSAID like this. Older adults may have an even greater risk of these serious gastrointestinal side effects.
Side effects are, however, patient specific. For additional information on this medication, go to. Lowell Sterler, RPh. A: Indomethacin (Indocin) is a non-steroidal anti-inflammatory drug (NSAID), used to treat inflammation from gout, and other conditions, such as arthritis, ankylosing spondylitis, tendonitis, or bursitis. Indomethacin does not lower uric acid levels in the body.
Indomethacin works by blocking certain prostaglandins from releasing substances in the body which cause inflammation. Diet and exercise are considered to be the best ways to reduce uric acid and should be tried first. If they fail, then an additional medication may need to be added. Ways to lower uric acid may include slowly losing weight, as a rapid reduction can actually induce a gout attack. Purines in the diet should be decreased, which includes avoiding alcohol.
Low fat dairy products, such as milk, yogurt, and cheese should be a part of the diet. Water is also important, as it can help clear uric acid from the body. Fruits which are low in purines include bananas, blueberries, cherries, and strawberries. Good choices in vegetables are cabbage, celery, kale, parsley, tomatoes, and all green, leafy vegetables. The prescription medication probenecid lowers uric acid by helping the body to pass it through the urine.
Other prescription medications, including Zyloprim (allopurinol) and Uloric (febuxostat) block the body from making uric acid. Uloric (febuxostat) is newer and has shown a benefit of not being as hard on the kidneys as the older medications. Although indomethacin is a common medication given to treat symptoms of gout, if diet and exercise are unable to reduce gout attacks, you may want to discuss other options with your doctor. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.
Patti Brown, PharmD. Food and Drug Administration (FDA) categorizes drugs based on their risk to the health of the baby. Indomethacin is considered pregnancy category C, meaning that it may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking indomethacin during the last 3 months of pregnancy may result in birth defects.
Do not take indomethacin during pregnancy unless your doctor has told you to. Consult your healthcare provider right away for specific recommendations.
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